C. elegans CEP-1/p53 and BEC-1 Are Involved in DNA Repair
نویسندگان
چکیده
منابع مشابه
C. elegans CEP-1/p53 and BEC-1 Are Involved in DNA Repair
p53 is a transcription factor that regulates the response to cellular stress. Mammalian p53 functions as a tumor suppressor. The C. elegans p53, cep-1, regulates DNA-damage induced germline cell death by activating the transcription of egl-1 and ced-13. We used the C. elegans model to investigate how, in the whole animal, different forms of DNA damage can induce p53-dependent versus p53-indepen...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0088828